Disulphide bonds and protein stability
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Thomas E. Creighton
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Article
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1988
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John Wiley and Sons
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English
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The properties of disulphide bonds relevant to their roles in stabilizing protein conformation are reviewed. Natural disulphides can stabilize folded conformations substantially, in some cases to much greater extents than would be expected from just entropic eflects on the unfolded state. The linkag