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Entire nucleotide sequence of mitochondrial DNA of MS/Ae mice

✍ Scribed by Shizuyo Sutou

Book ID
101264423
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
480 KB
Volume
28
Category
Article
ISSN
0893-6692

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✦ Synopsis

j a p a n The entire nucleotide sequence of mitochondrial DNA of MS/Ae mice was determined. It consists of 16,300 bases, with 15 sites being different from the known 16,295 base sequence of mitochondrial DNA derived from L cells of C3H mice (accession no. V0071 1). The MS/Ae strain is a derivative of CDl mice; these 15 sites in mitochondrial DNA from CD-1 mice were also determined. N o difference was found, strongly suggesting that mitochon-dria of MS/Ae and CD-1 mice have the same DNA sequence and indicating that the high sensitivity of MS/Ae mice to mutagens compared to C D l mice is not dependent on genes coded by mitochondrial DNA.

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