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Enteric viral pathogens in children with inflammatory bowel disease

✍ Scribed by Kaija-Leena Kolho; Päivi Klemola; Marja-Leena Simonen-Tikka; Marja-Liisa Ollonen; Merja Roivainen

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
63 KB
Volume
84
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

The causes of exacerbations of inflammatory bowel disease (IBD) are unknown. The presence of RNA of an enterovirus, norovirus GI, norovirus GII, rotavirus, astrovirus, and sapovirus was sought in stool samples of 50 children (median age 12.9 years) undergoing gastrointestinal endoscopies for IBD or its exclusion (Crohn's disease n = 18, ulcerative colitis n = 13, indeterminate colitis n = 2, non‐IBD n = 17). Viral RNA was found in three fecal samples (norovirus GII n = 2, sapovirus n = 1), all in children without IBD. Therefore, enteral viruses may play only a minor role in IBD. J. Med. Virol. 84:345–347, 2012. © 2011 Wiley Periodicals, Inc.

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