Entacapone and selegiline with l-dopa in patients with Parkinson's disease: an interaction study
✍ Scribed by J Lyytinen; S Kaakkola; A Gordin; E.-R Kultalahti; H Teräväinen
- Book ID
- 117751664
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 160 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1353-8020
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We compared the neuropsychological performance of patients with Parkinson's disease who were young at onset of the disease (mean age, 41.4 years) and had received prolonged L-dopa treatment (mean, 52.1 months) with nontreated patients of the same age. A similar comparison was made for patients who w
## Abstract Dyskinesia is a frequent and disabling side effect in patients with Parkinson's disease treated with chronic dopatherapy. Preclinical data in the 1‐methyl‐4‐phenyl‐1,2,3,6,‐tetrahydropyridine (MPTP) monkey suggest that alpha‐2 antagonists may reduce dihydroxyphenylalanine (L‐DOPA)‐induc