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Impaired transmethylation potential in Parkinson's disease patients treated with l-Dopa

โœ Scribed by Maria Luigia De Bonis; Alessandro Tessitore; Maria Teresa Pellecchia; Katia Longo; Anna Salvatore; Antonio Russo; Diego Ingrosso; Vincenzo Zappia; Paolo Barone; Patrizia Galletti; Gioacchino Tedeschi


Book ID
116771872
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
276 KB
Volume
468
Category
Article
ISSN
0304-3940

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## Abstract The effect of selegiline (Lโ€deprenyl) on plasma catecholamines, clinical response, and drug tolerability was studied in 13 patients with Parkinson's disease (PD) treated with Lโ€Dopa/benserazide and entacapone, a peripheral catecholโ€__O__โ€methyltransferase (COMT) inhibitor, in a placeboโ€