ent-Labdane Diterpenoid Lactone Stereoisomers from Andrographis paniculata
β Scribed by Zhu, Huajie; Wang, Rui; Zhou, Kailan; Jing, Yongkui; Qiu, Feng; Chen, Lixia
- Book ID
- 115445547
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 90 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0163-3864
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Four C(8),C(12)-diastereoisomers, (8S,12S)-isoandrographolide (1), (8S,12R)-isoandrographolide (2), (8R,12R)-isoandrographolide (3), and (8R,12S)-isoandrographolide (4) were isolated from the aerial parts of Andrographis paniculata. The structures of the new compounds 1 -3 were established on the ba
Nine new ent-labdane-type diterpenoids (1 -9), mostly in the form of the corresponding 16,15-lactones, were isolated from the 85%-EtOH extract of the aerial parts of Andrographis paniculata NEES., together with nine known compounds (10 -18). Their structures were deduced by in-depth NMR spectroscopy