Enigmatic conflict of clinical and molecular diagnosis in Duchenne/Becker muscular dystrophy
β Scribed by V. Dubowitz
- Book ID
- 116792756
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 39 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0960-8966
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Duchenne muscular dystrophy (DMD) is a progressive and lethal neuromuscular disorder caused by a defective gene on the X chromosome. There is no effective treatment and the biochemical defect is yet unknown. Mapping of the DMD locus to band Xp21 in the short arm of the X chromosome has given rise to
Recent advances in molecular genetics have led to the isolation of the gene defective in patients with Duchenne and Becker's muscular dystrophy and the characterization of its protein product, dystrophin. In this communication, the developments culminating in the identification of the Duchenne muscu