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Enhancing Gene Targeting with Designed Zinc Finger Nucleases

โœ Scribed by Bibikova, M.


Book ID
111910915
Publisher
American Association for the Advancement of Science
Year
2003
Tongue
English
Weight
49 KB
Volume
300
Category
Article
ISSN
0036-8075

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Gene targeting using zinc finger nucleas
โœ Porteus, Matthew H; Carroll, Dana ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 239 KB
Gene targeting using zinc finger nucleas
โœ Porteus, Matthew H; Carroll, Dana ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 239 KB

The ability to achieve site-specific manipulation of the mammalian genome has widespread implications for basic and applied research. Gene targeting is a process in which a DNA molecule introduced into a cell replaces the corresponding chromosomal segment by homologous recombination, and thus presen