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Enhancement of the polycation-mediated DNA uptake and cell transfection with Pluronic P85 block copolymer

✍ Scribed by Irina Astafieva; Irina Maksimova; Eugenii Lukanidin; Valery Alakhov; Alexander Kabanov


Book ID
115932553
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
557 KB
Volume
389
Category
Article
ISSN
0014-5793

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Novel block copolymer (PPDO/PLLA-b-PEG):
✍ Shanta Raj Bhattarai; Ho-Keun Yi; Narayan Bhattarai; Pyoung Han Hwang; Hak Yong 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 341 KB

The cationic lipid mediated uptake of plasmid DNA by cells in monolayer culture was signiWcantly enhanced with an aqueous solution of the block copolymer poly(p-dioxanone-co-L-lactide)-b-poly(ethylene glycol) (PPDO/PLLA-b-PEG). Plasmid uptake studies with DNA encoding the -galactosidase gene and cyt