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Enhancement of selective attention and memory retrieval after blockade of alpha 2 adrenoceptors

✍ Scribed by S.J. Sara


Book ID
118394651
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
59 KB
Volume
20
Category
Article
ISSN
0166-4328

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The chiral synthesis of the potent and selective alpha-2A antagonist, BRL 48962, is described. Evaluation of BRL 48962 at cloned human alpha-adrenoceptors indicates that this antagonist has a selectivity in the order of 30-fold for the alpha-2A subtype.