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Enhancement of phage-mediated gene transfer by nuclear localization signal

✍ Scribed by Teruo Akuta; Akiko Eguchi; Hajime Okuyama; Takao Senda; Hachiro Inokuchi; Yosuke Suzuki; Emi Nagoshi; Hiroyuki Mizuguchi; Takao Hayakawa; Katsuo Takeda; Mamoru Hasegawa; Mahito Nakanishi


Book ID
117052624
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
208 KB
Volume
297
Category
Article
ISSN
0006-291X

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Effect of peptides bearing nuclear local
✍ Maayan Duvshani-Eshet; Hadas Keren; Shira Oz; Inna S. Radzishevsky; Amram Mor; M πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 370 KB

## Abstract ## Background One of the major limitations of nonviral gene delivery methods is nuclear transport of plasmid DNA (pDNA). Peptides bearing nuclear localization signal (NLS) were shown to mediate nuclear import of macromolecules. We have explored the use of cell‐permeable peptides (CPP)