𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enhancement of Gemcitabine-Induced Apoptosis by Restoration of p53 Function in Human Pancreatic Tumors

✍ Scribed by Cascalló, Manel; Calbó, Joaquim; Capellà, Gabriel; Fillat, Cristina; Pastor-Anglada, Marçal; Mazo, Adela

Book ID
120518175
Publisher
S. Karger AG
Year
2005
Tongue
English
Weight
741 KB
Volume
68
Category
Article
ISSN
0030-2414

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Restoration of wild-type p53 function in
Restoration of wild-type p53 function in human cancer: Relevance for tumor therapy
✍ Gianluca Bossi; Ada Sacchi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 480 KB

## Abstract ## Background. In the majority of human cancers, the tumor suppressor activity of p53 is impaired because of mutational events or interactions with other proteins (ie, MDM2). The loss of p53 function is responsible for increased aggressiveness of cancers, while tumor chemoresistance an

Enhancement of radiation-induced regrowt
Enhancement of radiation-induced regrowth delay by gemcitabine in a human tumor xenograft model
✍ Marion A. Joschko; Lorraine K. Webster; Janice Groves; Kally Yuen; Manuela Palat πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 545 KB

Gemcitabine, a cytidine nucleoside analogue, has schedule-dependent antitumor activity in vitro and in vivo. Gemcitabine also has dose-and time-dependent radiosensitization properties in vitro. Thus it may have therapeutic application in combination with radiation. The aims of this study were to inv