𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human lung cancer cell lines


Book ID
123431362
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
166 KB
Volume
7
Category
Article
ISSN
0169-5002

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Enhancement of fluorinated pyrimidine-in
✍ Chun-Ming Tsai; Adi F. Gazdar; Carmen Allegra; Reury-Perng Perng; Barnett S. Kra πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 French βš– 535 KB

Reduced folates have been shown to increase the cytotoxicity of 5-fluorouracil (FUra) by stabilizing the fluorodeoxyuridine monophosphate:thymidylate synthase complex, thus increasing the block in the DNA synthetic pathway. Using an in vitro tetrazolium colorimetric ( M T Q cytotoxic assay, we teste