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Enhancement by interleukin-1 beta of gastric carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine in Wistar rats: a possible mechanism for Helicobacter pylori-associated gastric carcinogenesis

✍ Scribed by Noriya Uedo; Masaharu Tatsuta; Hiroyasu Iishi; Miyako Baba; Hiroyuki Yano; Ryu Ishihara; Koji Higashino; Shingo Ishiguro


Book ID
117467882
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
268 KB
Volume
198
Category
Article
ISSN
0304-3835

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The effect of tyrosine methyl ester (TME) on the incidence, number, and histological types of gastric cancers induced by N-methyl-N'-nitro-N-nitroroguanidine (MNNG) was investigated in male Wistar rats. Rats were subcutaneously given TME, 5 I 2 mg/kg body weight, every other day after 20 weeks of or