Enhancement and inhibition of luminol chemiluminescence by phenolic acids

✍ Scribed by Díaz, A. Navas ;Sánchez, F. García ;García, J. A. GonzáLez

• Publisher: John Wiley and Sons
• Year: 1995
• Weight: 603 KB
• Volume: 10
• Category: Article
• ISSN: 0884-3996
• DOI: 10.1002/bio.1170100306

✦ Synopsis

We explored the behaviour o f a series o f phenolic acids used as enhancers or inhibitors of luminol chemiluminescence by three different methods t o determine if behaviour was associated with phenolic acid structure and redox character. All the phenolic acids inhibited chemiluminescence when hexacyanoferrate( 111) was reacted with the phenolic acids before adding luminol. The redox character o f these compounds was clearly related t o structure. When hexacyanoferrate( Ill)-luminol-02 chemiluminescence was initiated by phenolic acid-luminol mixtures some phenolic acids behaved as enhancers o f chemiluminescence, and others as inhibitors. We propose a mechanism t o explain these findings. We found direct relationships between the redox character of the phenolic acids and the enhancement or inhibition o f the chemiluminescence o f the luminol-H202-peroxidase system and w e propose mechanism t o explain these phenomena.