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Enhanced tyrosine phosphorylation of striatal NMDA receptor subunits: effect of dopaminergic denervation and l-DOPA administration

✍ Scribed by Justin D Oh; David Russell; Christina L Vaughan; Thomas N Chase


Book ID
114004444
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
586 KB
Volume
813
Category
Article
ISSN
0006-8993

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Denervation-induced supersensitivity of the striatal dopamine receptors can be quantified by the turning behaviour induced by apomorphine. With this experimental model we found that high-dose L-dopa/carbidopa administration reduced this supersensitivity. This effect was seen on the 1st day and did n