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Enhanced Sister-Chromatid Exchange Rate in Human Lymphocytes Exposed to 17β Estradiol in Vitro

✍ Scribed by Ninoslav Djelic; Dijana Djelic


Book ID
114179936
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
230 KB
Volume
33
Category
Article
ISSN
0188-4409

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The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. The addition of inorganic trivalent arsenic (Na2HAsO4) 10-6M and 2 x 10-6M induces a significant and dose-dependent increase of SCE. This phenomenon is as sensitiv