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Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)

โœ Scribed by Madry, H; Kaul, G; Cucchiarini, M; Stein, U; Zurakowski, D; Remberger, K; Menger, M D; Kohn, D; Trippel, S B


Book ID
120631681
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
311 KB
Volume
12
Category
Article
ISSN
0969-7128

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Local stimulation of articular cartilage
โœ Gunter Kaul; Magali Cucchiarini; David Arntzen; David Zurakowski; Michael D. Men ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 461 KB

## Background: Defects of articular cartilage are an unsolved problem in orthopaedics. in the present study, we tested the hypothesis that gene transfer of human fibroblast growth factor 2 (fgf-2) via transplantation of encapsulated genetically modified articular chondrocytes stimulates chondrogene