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Enhanced permeation and stratum corneum structural alterations in the presence of dithiothreitol

✍ Scribed by Cynthia Y Goates; Kristine Knulson

Book ID
115730565
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
969 KB
Volume
1153
Category
Article
ISSN
0005-2736

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The purpose of this study was to evaluate structure-permeability relationships for chemicals through stratum corneum (SC) and viable epidermis/dermis (VED). In vitro skin permeation of ten compounds through excised rat skin was analyzed based on a two-layer diffusion model and the diffusion coeffici