Structureโpermeability relationship anal
โ
Koji Yamaguchi; Tetsuya Mitsui; Yoshinori Aso; Kenji Sugibayashi
๐
Article
๐
2008
๐
John Wiley and Sons
๐
English
โ 190 KB
The purpose of this study was to evaluate structure-permeability relationships for chemicals through stratum corneum (SC) and viable epidermis/dermis (VED). In vitro skin permeation of ten compounds through excised rat skin was analyzed based on a two-layer diffusion model and the diffusion coeffici