✦ LIBER ✦

Enhanced metastases of a mouse carcinoma after in vitro treatment with murine interferon gamma

✍ Scribed by Pijamila Ramani; Frances R. Balkwill

Publisher: John Wiley and Sons
Year: 1987
Tongue: French
Weight: 546 KB
Volume: 40
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910400621

No coin nor oath required. For personal study only.

✦ Synopsis

Fluorescence-activated cell sorter (FACS) analysis

COLON 26 cells (10 X lo6), control or pre-treated with rHuIFN-aA/D or rMuIFN-y, were incubated with PBS: 1 % BSA:0.2% sodium azide or loop1 monoclonal antibody for 45 min at 4°C. The cells were washed 3 times with PBS: 1 % BSA:0.2% sodium azide and incubated further for 30 min with 50p.1 of FITC-conjugated rabbit anti-mouse IgG diluted 1:5 in D.W. (Cappel, Dynatech, Billingshurst, UK). After 3 addi-

MATERIAL AND METHODS

Mice

/ + female mice, BALB/c nu/nu female mice, and beige nu/ cence was andysed On FAcs. nu female mice. All the mice were bred at the ICRF Animal Unit, Clare Hall, UK, under specific-pathogen-free conditions.

Three groups of 6to g-week-old mice were used: BALB/c tional washes with PBS: 1 % BSA:0.2 % azide, d l fluores-

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