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Enhanced intrinsic migration of aggressive breast cancer cells by inhibition of Rac1 GTPase

โœ Scribed by Yufeng Zuo; Sarah-Kim Shields; Chandan Chakraborty

Book ID
116293818
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
435 KB
Volume
351
Category
Article
ISSN
0006-291X

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Cdc42 negatively regulates intrinsic mig
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โœ Yufeng Zuo; Yuexiu Wu; Chandan Chakraborty ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 668 KB

## Abstract The small GTPase Cdc42 has been implicated as an important regulator of cell migration. However, whether Cdc42 plays similar role in all cancer cells irrespective of metastatic potential remains poorly defined. Here, we show by using three different breast cancer cell lines with differe