Enhanced immunogenicity of hepatitis B surface antigen by insertion of a helper T cell epitope from tetanus toxoid
โ Scribed by Murty V Chengalvala; Ramesh A Bhat; Bheem M Bhat; Steven K Vernon; Michael D Lubeck
- Book ID
- 117433099
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 245 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0264-410X
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๐ SIMILAR VOLUMES
Microencapsulated liposome systems (MELs) were investigated as a potential immunization carrier for a recombinant 22-nm hepatitis B surface antigen (HBsAg) particle. MELs were prepared by first entrapping the HBsAg particles within liposomes composed of phosphatidylcholine:cholesterol (1:1 molar rat
The human hepatoblastoma-derived cell line HB6 I I secretes hepatitis-B surface antigen (HBsAg) and hepatitis-B e antigen (HBeAg) into the medium. Hepatitis-B-virus(HBV) DNA integrated into the cellular genome was found to be hypermethylated. When the cells were treated with 5-azacytidine for 3 days