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Enhanced expression of the complement factor H mRNA in proliferating human RPE cells

✍ Scribed by Norbert Kociok; Antonia M. Joussen

Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
373 KB
Volume
248
Category
Article
ISSN
0065-6100

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Complement regulatory proteins present on the surface of various mammalian cells play an important role in controlling homologous lysis, by interacting with C3 (and usually C4). These proteins have a similar structural motif ("short consensus repeat") (Reid, K.B.