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A novel, complement factor H-related regulatory protein expressed on the surface of human B cell lines

✍ Scribed by Anna Erdei; Nathalie Julen; Peter Marschang; Elisabeth Feifel; Krisztina Kerekes; Manfred P. Dierich

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
697 KB
Volume
24
Category
Article
ISSN
0014-2980

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✦ Synopsis

Complement regulatory proteins present on the surface of various mammalian cells play an important role in controlling homologous lysis, by interacting with C3 (and usually C4). These proteins have a similar structural motif ("short consensus repeat") (Reid, K.B.

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## Abstract Receptors for the third component of complement (C3) were demonstrated on the surface of established human lymphoid cell lines by a membrane fluorescence test with FITC‐ or TRITC‐conjugated antibodies against human C3. Two‐color fluorescence staining of EBV receptors and C3 receptors sh