Enhanced caspase activity during ethanol-induced apoptosis in rat cerebellar granule cells
โ Scribed by Jan Oberdoerster; Richard A Rabin
- Book ID
- 114017638
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 370 KB
- Volume
- 385
- Category
- Article
- ISSN
- 0014-2999
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Caspase-3 activity increased dramatically in cytosolic extracts of rat cerebellar granule cells exposed to apoptotic conditions (basal medium Eagle (BME) containing 5 mM K ุ without serum) when assayed with Ac-DEVD-amc, but not with Ac-YVAD-afc, a preferred substrate for caspase-1. This provided a b
The multicatalytic protease complex or proteasome is a fundamental nonlysosomal tool that the cell uses to process or degrade proteins at a fast rate through the ubiquitin and ATP-dependent proteolytic pathway. Examples of these important proteins include the tumor suppressor protein p53, various cy