## Abstract Pycnogenol® (PYC), a patented combination of bioflavonoids extracted from the bark of French maritime pine (__Pinus maritima__), inhibits apoptosis and necrosis of developing neurons exposed acutely to ethanol (EtOH). The present study shows that the protective mechanisms of PYC in EtOH
Pycnogenol® and vitamin E inhibit ethanol-induced apoptosis in rat cerebellar granule cells
✍ Scribed by Siler-Marsiglio, Kendra I. ;Shaw, Gerry ;Heaton, Marieta B.
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 628 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-3034
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The nuclear factor (NF)‐κB family of transcription factors plays important roles in the regulation of many activities of neuronal cells, such as synaptic transmission, inflammation, neuroprotection, and neurotoxicity. In resting cells, NF‐κB activity is present both in the cytoplasm, as
The endogenous polyamines have been extensively studied with respect to their role in cellular death mechanisms, although the results are contradictory. In contrast, their primary metabolites, the N-acetyl polyamines, have not been much studied. It has been hypothesized that the N-acetyl metabolites
We have investigated the involvement of c-Jun in cell death induced by exposure of primary cultures of murine cerebellar granule cells to the glutamate receptor agonist kainate (KA) and evaluated its possible use as a marker for apoptosis. Using cerebellar granule cell neurones from postnatal day 7
## Abstract Gambierol is a marine polyether ladder toxin derived from the dinoflagellate __Gambierdiscus toxicus__. To date, gambierol has been reported to act either as a partial agonist or as an antagonist of sodium channels or as a blocker of voltage‐dependent potassium channels. In this work, w