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Enhanced bioavailability after oral and pulmonary administration of baicalein nanocrystal

✍ Scribed by Jianjun Zhang; Huixia Lv; Kun Jiang; Yuan Gao

Book ID
113655608
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
721 KB
Volume
420
Category
Article
ISSN
0378-5173

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## Abstract Paclitaxel is a substrate of the efflux transporters such as P‐glycoprotein, and is mainly metabolized by the liver. Schisandrol B (Sch B), one of the active components in Schisandra, has been reported to be able to inhibit the activity of P‐gp and CYP3A. It might be possible that Sch B