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Enhanced Antitumor Activity and Reduced Toxicity of 1,3-Bis(2-chloroethyl)-1-nitrosourea Administered in Lipid Microspheres to Tumor-bearing Mice

✍ Scribed by Takenaga, Mitsuko ;Igarashi, Rie ;Tsuji, Hiroaki ;Mizushima, Yutaka


Book ID
108579736
Publisher
Wiley (Blackwell Publishing)
Year
1993
Tongue
English
Weight
458 KB
Volume
84
Category
Article
ISSN
0910-5050

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## Abstract The effects of single‐agent therapy with two clinically useful drugs, 5‐fluorouracil (5‐FU) and 1‐3‐bis‐(2‐chloro‐ethyl)‐1‐nitrosourea (BCNU) against nine human colorectal tumors (rectum T 157 and T 348, lung metastasis T 84, lymph‐node metastasis T 245, colon, T 183, T 219, T 347, T 36