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Engagement of CD40 lowers the threshold for activation of resting B cells via antigen receptor

✍ Scribed by Kay Wheeler; John D. Pound; John Gordon; Roy Jefferis


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
371 KB
Volume
23
Category
Article
ISSN
0014-2980

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## Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes To identify the ligand for the B cell-associated antigen CD40, we constructed a chimeric immunoglobulin molecule where the extracellular porti