Energy Compensation in the Crabtree Effect with Ehrlich Ascites Carcinoma Cells
โ Scribed by IBSEN, K. H.; COE, E. L.; McKEE, R. W.
- Book ID
- 109601299
- Publisher
- Nature Publishing Group
- Year
- 1959
- Tongue
- English
- Weight
- 114 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0028-0836
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๐ SIMILAR VOLUMES
## Abstract The addition of glucose to ELD and ELT/B1 mouse ascites tumor cell suspensions caused a 2.3โfold increase in the phosphorylation state ratio, (ATP)/(ADP)(Pi), because of a decrease in the intracellular Pi concentration. The addition of glucose to these cell suspensions has been reported
The main purpose of the present investigation was to study the effect of cloturin on aerobic glycolysis, endogenous and exogenous respiration and the level of ATP in both Ehrlich ascites carcinoma (EAC) and P388 murine leukaernia cells incubated in vitro. Also its effect on the level of total (T-SH)
## ABSTRACT A change in glucose concentration in an Ehrlich ascites carcinoma cell suspension from 0.1 mM to 20 mM causes a more than 50โfold stimulation of the rate of ribosomal RNA synthesis. Such an effect occurs without any dramatic effect on the rate of protein synthesis in cells. This process