Glucose strongly stimulates rate of the rRNA synthesis in Ehrlich ascites carcinoma cells.

✍ Scribed by I.M. Buzhurina; N.G. Chernaya; M.A. Panov

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 129 KB
• Volume: 18
• Category: Article
• ISSN: 1065-6995
• DOI: 10.1006/cbir.1994.1095

✦ Synopsis

ABSTRACT

A change in glucose concentration in an Ehrlich ascites carcinoma cell suspension from 0.1 mM to 20 mM causes a more than 50‐fold stimulation of the rate of ribosomal RNA synthesis. Such an effect occurs without any dramatic effect on the rate of protein synthesis in cells. This process parallels a decrease in intracellular pH which may be a reason of Na^+^/H^+^‐antiport activation.