Energetics of Na+-dependent amino acid co-transport in Ehrlich ascites tumor cells
β Scribed by W.David Dawson; Thomas C. Smith
- Book ID
- 115728164
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 696 KB
- Volume
- 897
- Category
- Article
- ISSN
- 0005-2736
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## Abstract Vincristine, other periwinkle alkaloids, and colchicine partially inhibit the energy dependent transport of Ξ±βaminoisobutyric acid in Ehrlich ascites tumor cells. The properties of this phenomenon were characterized in detail for vincristine. Maximum depression of the steadyβstate intra
## Abstract The effects of H^+^ on the kinetics of Ξ±βaminoisobutyric acid (AIB) influx in Ehrlich ascites tumor cells have been investigated at different external Na^+^ concentrations. Elevation of [H^+^] in the presence of both high (154 mEq/l) and low (10 mEq/l) external Na^+^ leads to decreases