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Endothelin-Stimulated Ca2+Mobilization by 3T3-L1 Adipocytes Is Suppressed by Tumor Necrosis Factor-α

✍ Scribed by Mark Yorek; Navin Jaipaul; Joyce Dunlap; Klaus Bielefeldt

Book ID
115567407
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
152 KB
Volume
361
Category
Article
ISSN
0003-9861

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## Abstract Amyloid precursor protein (APP) has been characterized as an adipocyte‐secreted protein that might contribute to obesity‐related insulin resistance, inflammation, and dementia. In the current study, regulation of APP by the proinflammatory and insulin resistance‐inducing cytokine tumor