Endothelin receptor antagonists and cerebral vasospasm
β Scribed by Michael Zimmermann; Volker Seifert
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 129 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0959-9851
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π SIMILAR VOLUMES
The synthesis and in vitro binding affinities of a series of thiophenesulfonamides as ET A selective endothelin receptor antagonists is described. The most potent inhibitor displayed an IC50 of 43 nM and 3 ktM to ET A and ETB receptors, respectively.
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