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Endothelin-1 Stimulates Cardiac Fibroblast Proliferation Through Activation of Protein Kinase C

✍ Scribed by Lucia Piacentini; Mary Gray; Norman Y Honbo; Jamila Chentoufi; Marina Bergman; Joel S Karliner

Book ID: 115632991
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 652 KB
Volume: 32
Category: Article
ISSN: 0022-2828
DOI: 10.1006/jmcc.2000.1109

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## Abstract Endothelin‐1 (ET‐1) is implicated in the fibrotic responses characterizing interstitial lung diseases, as well as in the airway remodeling process occurring in asthma. Within such a context, the aim of our study was to investigate, in primary cultures of normal human lung fibroblasts (N