## Abstract Many reports have shown that matrix metalloproteinase (MMP)‐9 plays an important role in brain inflammation and diseases. In our previous study, bradykinin (BK) has been shown to induce proMMP‐9 expression via MAPKs and NF‐κB in rat brain astrocytes (RBA‐1). However, the molecular mecha
Endothelin-1 enhances cell migration via matrix metalloproteinase-9 up-regulation in brain astrocytes
✍ Scribed by Hui-Hsin Wang; Hsi-Lung Hsieh; Cheng-Ying Wu; Chuen-Mao Yang
- Book ID
- 111183949
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 836 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Upregulation of matrix metalloproteinases (MMPs), especially MMP‐9, by oxidized low‐density lipoprotein (oxLDL) is implicated in many inflammatory diseases including brain injury. However, the signaling mechanisms underlying oxLDL‐induced MMP‐9 expression in astrocytes largely remain un
Hepatocyte growth factor/scatter factor (HGF/SF) contributes to the malignant progression of human gliomas. We investigated the effect of HGF/SF on matrix metalloproteinase-2 (MMP-2), membrane type 1 matrix metalloproteinase (MT1-MMP) and tissue inhibitors of metalloproteinases (TIMPs), expressions
## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor