## Abstract Upregulation of matrix metalloproteinases (MMPs), especially MMP‐9, by oxidized low‐density lipoprotein (oxLDL) is implicated in many inflammatory diseases including brain injury. However, the signaling mechanisms underlying oxLDL‐induced MMP‐9 expression in astrocytes largely remain un
✦ LIBER ✦
Oxidized Low-Density Lipoprotein-Induced Matrix Metalloproteinase-9 Expression via PKC-δ/p42/p44 MAPK/Elk-1 Cascade in Brain Astrocytes
✍ Scribed by Hui-Hsin Wang; Hsi-Lung Hsieh; Cheng-Ying Wu; Chuen-Mao Yang
- Book ID
- 107678036
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 820 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1029-8428
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## Abstract Bradykinin (BK), an inflammatory mediator, has been shown to induce cytosolic phospholipase A~2~ (cPLA~2~) expression implicating in inflammatory responses in various cell types. However, the detailed mechanisms underlying BK‐induced cPLA~2~ expression in astrocytes remain unclear. RT‐P