Endothelin-1 and diabetic complications: Focus on the vasculature
β Scribed by Adviye Ergul
- Book ID
- 119346849
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 294 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1043-6618
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Immunocytochemical localization of big endothelin-1 (big ET-1), ET-1, and ET receptor A and B (ET A and ET B ), and gene expression of prepro ET-1 mRNA were examined on the rat liver vasculature. Immunoreactivities for big ET-1 and ET-1 were preferentially seen along the endothelium of interlobular
## Abstract Endothelinβ1 is a vasoactive peptide produced by the vascular endothelium. It is one of the most potent endogenous vascular smooth muscle constrictors. Two subtypes of the endothelin receptor have been cloned and sequenced and denoted endothelinβA and endothelinβB. The aim of this study