𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Endothelin-1: A Potent Vasoactive Peptide

✍ Scribed by Schini, Valérie B. ;Vanhoutte, Paul M.

Book ID
114801684
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
777 KB
Volume
69
Category
Article
ISSN
0901-9928

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

1-benzyl-3-thioaryl-2-carboxyindoles as
1-benzyl-3-thioaryl-2-carboxyindoles as potent non-peptide endothelin antagonists
✍ Amy M. Bunker; Jeremy J. Edmunds; Kent A. Berryman; Donnelle M. Walker; Michael 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 242 KB

Endothelin-1 is a potent vasoconstrictor which is thought to be involved in many human disease states. We have developed a series of indole non-peptide endothelin antagonists which display nanomolar receptor affinity. The representative compound from this series is PD 159433 ( 22), an ETA selective

1,3-diaryl-2-carboxyindoles as potent no
1,3-diaryl-2-carboxyindoles as potent non-peptide endothelin antagonists
✍ Amy M Bunker; Jeremy J Edmunds; Kent A Berryman; Donnelle M Walker; Michael A Fl 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 311 KB

Endothelin-1 is a potent vasoconstrictor that is thought to be involved in many human disease states. We have developed a series of indole non-peptide endothelin antagonists including PD 159110 (31), an ETA selective antagonist, and PD 159020 (37), a non-selective ETA/ETB antagonist. The discovery,