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Endothelial regulation of coronary vascular tone in vitro: contribution of endothelin receptor subtypes and nitric oxide

✍ Scribed by John Pernow; Agnes Modin

Book ID
115888362
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
549 KB
Volume
243
Category
Article
ISSN
0014-2999

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Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of thi