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Crosstalk Between Endothelin and Nitric Oxide in the Control of Vascular Tone

✍ Scribed by Michel Lavallée; Masayuki Takamura; Robert Parent; Eric Thorin


Book ID
110301627
Publisher
Springer
Year
2001
Tongue
English
Weight
191 KB
Volume
6
Category
Article
ISSN
1382-4147

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Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of thi