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Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage and cerebral vasospasm

✍ Scribed by Khurana, Vini G.; Sohni, Youvraj R.; Mangrum, Wells I.; McClelland, Robyn L.; O'Kane, Dennis J.; Meyer, Fredric B.; Meissner, Irene


Book ID
110088658
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
301 KB
Volume
24
Category
Article
ISSN
0271-678X

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Simvastatin attenuation of cerebral vaso
✍ Takashi Sugawara; Robert Ayer; Vikram Jadhav; Wanqiu Chen; Tamiji Tsubokawa; Joh πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 823 KB

## Abstract The mechanisms involved in simvastatin‐mediated attenuation of cerebral vasospasm after subarachnoid hemorrhage (SAH) are unclear. We investigated the role of the phosphatidylinositol 3‐kinase/Akt (PI3K/Akt) pathway and endothelial nitric oxide synthase (eNOS) in the cerebral vasculatur