Endothelial Cell Dysfunctions

✍ Scribed by Maya Simionescu (auth.), Nicolae Simionescu, Maya Simionescu (eds.)

• Publisher: Springer US
• Year: 1992
• Tongue: English
• Leaves: 562
• Edition: 1
• Category: Library

✦ Synopsis

Noted experts survey and evaluate the latest research in the growing field of endothelial cell involvement in the initiation and development of various diseases. Research-oriented chapters span a diversity of topics, including endothelial cell response to various injuries and its crucial role in inflammation, immunity, viral infection, hypertension, hyperlipidemia, atherosclerosis, diabetes mellitus, neoplasia, and metastasis.

✦ Table of Contents

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Endothelial Cell Response to Normal and Abnormal Stimuli....Pages 3-9
Interactions of Matrix Components and Soluble Factors in Vascular Responses to Injury....Pages 11-30
Endothelial Cell Regrowth....Pages 31-48
Modulation of Fibronectin and Thrombospondin Synthesis and mRNA Levels by Heparin in Human Endothelial and Smooth Muscle Cell Cultures....Pages 49-63
Dysfunction of the Release of Endothelium-Derived Relaxing Factor....Pages 65-102
Modulation of Endothelial Paracellular Permeability....Pages 103-126
Front Matter....Pages 127-127
Endothelial-Leukocyte Adhesion Molecules in Acute Inflammation and Atherogenesis....Pages 129-140
Leukocyte-Mediated Endothelial Injury....Pages 141-152
Endothelial Cell Adhesive Interactions....Pages 153-168
Modulation of Endothelial Cell Proliferation by Monocyte-Derived Cytokines....Pages 169-181
Recent Insights into the Mechanisms of Vascular Injury....Pages 183-189
The Role of Endothelium in the Pathophysiology of Rheumatoid Inflammation....Pages 191-199
Mechanisms of Neutrophil Migration across Endothelium....Pages 201-231
Endothelial Permeability in Inflammation....Pages 233-242
Front Matter....Pages 243-243
Response of Human Vascular Cells to Viral Infection....Pages 245-266
Front Matter....Pages 267-267
Changes of Arterial Endothelial Cells in Chronic Hypertension with Special Reference to Regressive Changes and Replication....Pages 269-282
Specific Platelet Mediators and the Abrupt Progression of Coronary Artery Stenoses....Pages 283-294
Endothelial Dysfunction and Atherosclerosis....Pages 295-307
Artery Wall Interactions in Early Atherogenesis....Pages 309-319
Endothelial Cell Dysfunction and Injury in Experimental Hyperlipidemic Atherogenesis....Pages 321-344
Front Matter....Pages 345-345
Brain Capillary Endothelial Transport of Insulin....Pages 347-362
Vascular Endothelium and Diabetes Mellitus....Pages 363-381
Cellular and Molecular Mechanism of Glucose-Induced Diabetic Microangiopathy....Pages 383-391
Front Matter....Pages 393-393
Role of the Vascular Endothelium in Cancer Metastasis....Pages 395-425
Endothelial Cell Heterogeneity....Pages 427-437
Organotypic Endothelial Cell Surface Molecules Mediate Organ Preference of Metastasis....Pages 439-454
The Microvascular Phases of Metastasis....Pages 455-475
Possible Relationship between Vascular Permeability Factors, Endothelial Cells, and Peritumoral Brain Edema....Pages 477-503
Front Matter....Pages 505-505
Effects of Polyunsaturated Fatty Acids in Endothelium....Pages 507-524
Modulation of Endothelial Coagulant Properties and Barrier Function by Factors in the Vascular Microenvironment....Pages 525-545
Parathyroid Endothelium....Pages 547-559
Back Matter....Pages 561-565

✦ Subjects

Pathology; Animal Anatomy / Morphology / Histology; Plant Sciences