## Abstract ## Background: Although tumor hypoxia has been associated with a more aggressive phenotype and lower cure rate, there is no consensus as to the method best suited for routine measurement. Binding of the chemical hypoxia marker, pimonidazole, and expression of the endogenous hypoxia mar
β¦ LIBER β¦
Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer
β Scribed by Michael I. Koukourakis; Alexandra Giatromanolaki; Alexandros Polychronidis; Costantinos Simopoulos; Kevin C. Gatter; Adrian L. Harris; Efthimios Sivridis
- Book ID
- 108583657
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 186 KB
- Volume
- 97
- Category
- Article
- ISSN
- 1347-9032
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## Abstract Herβ2/__neu__ (__erb__Bβ2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Herβ2/__neu__