𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Gene expression of 5-fluorouracil metabolic enzymes in primary colorectal cancer and corresponding liver metastasis

✍ Scribed by Mikito Inokuchi; Hiroyuki Uetake; Yoshinori Shirota; Hiroyuki Yamada; Masayuki Tajima; Kenichi Sugihara

Book ID
105991908
Publisher
Springer
Year
2004
Tongue
English
Weight
262 KB
Volume
53
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

5-fluorouracil-related gene expression l
5-fluorouracil-related gene expression levels in primary colorectal cancer and corresponding liver metastasis
✍ Hidekazu Kuramochi; Kazuhiko Hayashi; Kazumi Uchida; Satoru Miyakura; Daisuke Sh 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 103 KB 👁 1 views

## Abstract Gene expression levels of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), thymidine phosphorylase (TP) and orotate phosphoribosyl transferase (OPRT) have been shown to be associated with response to 5‐fluorouracil‐based therapies. Analyzing these gene expression levels

Predicting 5-fluorouracil chemosensitivi
Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: Three-gene expression model predicts clinical response
✍ Ryusei Matsuyama; Shinji Togo; Daisuke Shimizu; Nobuyoshi Momiyama; Takashi Ishi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 131 KB 👁 1 views

## Abstract We identified genes related to 5‐fluorouracil (5‐FU) sensitivity in colorectal cancer and utilized these genes for predicting the 5‐FU sensitivity of liver metastases. Eighty‐one candidate genes involved in 5‐FU resistance in gastric and colon cancer cell lines were previously identifie

Synergistic effects of docetaxel and S-1
Synergistic effects of docetaxel and S-1 by modulating the expression of metabolic enzymes of 5-fluorouracil in human gastric cancer cell lines
✍ Yoshiyuki Wada; Kazuhiro Yoshida; Takahisa Suzuki; Hirozumi Mizuiri; Kazuo Konis 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 412 KB 👁 1 views

## Abstract We have recently demonstrated in a Phase I/II study that combination chemotherapy with docetaxel (TXT) and S‐1 is active against metastatic gastric carcinomas. To elucidate the mechanisms underlying the synergistic effects of these drugs, both the growth inhibitory effects and the expre

Role of IKK and oscillatory NFκB kinetic
Role of IKK and oscillatory NFκB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells
✍ Ryuichi Fukuyama; Kwok Peng Ng; Muzaffer Cicek; Clare Kelleher; Roxana Niculaita 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 422 KB

## Abstract Nuclear factor kappa B (NFκB) is a central participant in the metastasis and chemoresistance of colorectal cancer (CRC). However, it is not fully understood to what extent NFκB contributes to induction of the metastasis‐associated matrix metalloprotease‐9 (__MMP‐9__) gene and sensitivit