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Endocytosis and exocytosis: Role of microfilaments and involvement of phospholipids in membrane fusion

✍ Scribed by Korn, Edward D. ;Bowers, Blair ;Batzri, Shmuel ;Simmons, Susan R. ;Victoria, Edward J.

Publisher
Wiley (John Wiley & Sons)
Year
1974
Tongue
English
Weight
835 KB
Volume
2
Category
Article
ISSN
0091-7419

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✦ Synopsis

Abstract

A brief description of endocytosis and exocytosis is followed by a discussion of the experimental approaches to the study of the initial events of endocytosis, the possible involvement of microfilaments, and in particular the possible role of membrane lipids in the events of membrane fusion. Recently developed model systems are also discussed.

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The transport of proteins across continuous capillary endothelium is believed to be mediated by micropinocytic vesicles which shuttle molecules between the lumenal and abluminal plasma membrane. We have studied the ability of capillary endothelial cells isolated from rat epididymal fat to endocytose