Perfluorosulfonic acid (PFSA) polymer membranes are widely used as electrolyte thin films to transport protons in proton exchange membrane (PEM) fuel cells. The mechanical degradation of the membrane represents a common failure mode that limits the operational life of the fuel cells. In the present
Effects of bivalent cations and proteins on thermotropic properties of phospholipid membranes: Implications for the molecular mechanism of fusion and endocytosis
β Scribed by Demetrios Papahadjopoulos
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 900 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0021-9797
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Vesicles having diameters from 20 to 200 nm were prepared from egg-yolk phosphatidylcholine (PC) and were separated as well as analyzed by methods that can be carried out with standard laboratory equipment. Gel-chromatography on Sephacryl S 1000 was adapted for expeditious size analysis of vesicles
## Purpose: To investigate the effect of plasticizers on the stability of protein formulations in the solid state and to apply these results to a study of mechanisms of protein stabilization by sugars in the solid sate. ## Methods: The igg1 antibody was formulated with either sucrose or trehalose