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✦   LIBER   ✦

Endocytic Capacities of Kupffer Cells Isolated from the Human Adult Liver

✍ Scribed by André Kirn; Annick Bingen; Anne-Marie Steffan; Marie-Thérèse Wild; Francoise Keller; Jacques Cinqualbre

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
758 KB
Volume
2
Category
Article
ISSN
0270-9139

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✦ Synopsis

Kupffer cells isolated from human adult livers and maintained in culture display the main structural features of macrophages. They are able to phagocytose latex particles and opsonized sheep erythrocytes in uitro. Vaccinia virus as well as Frog Virus 3 are taken up and uncoated in cultured Kupffer cells. Such a model may be used advantageously for studying different problems in liver physiopathology.

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