Triglyceride synthesis and hepatitis C v
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Catherine Schuster; Mathieu Lefèvre; Thomas F. Baumert
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Article
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2011
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John Wiley and Sons
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English
β 309 KB
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection. DGAT1 interacts with the viral nucleocapsid core and is required for the tr